The aim of the study is to assess the effects of hyperbaric oxygenotherapy in post stroke aphasia during the chronic phase. We report a case series of 3 patients suffering from postischemic stroke Broca’s aphasia, all hospitalized and taken in charge in the neurology department of the military hospital of Tunis, between 2018 and 2020. Each patient had around 30 to 40 sessions of Hyperbaric Oxygenotherapy (HBO). The evaluation of the language was performed with the Montreal Toulouse MT 86 using the Arabic version before and after HBO.
Several mechanisms enable the human body to maintain an adequate oxygen supply [6]. The systemic sensing and response to hypoxia include (a) carotid body glomus, a chemosensor in the arterial circulation that can increase the ventilation rate, (b) and the neuroepithelial bodies (NEBs), which are clusters of cells exposed to the airway lumen at branching points, innervated by the Vagus nerve which dilate the pulmonary arteries to optimize the ventilation–perfusion exchange.
HBOT uses air pressure 2 to 3 times higher than the atmospheric pressure around us, helping our lungs gather much more oxygen than would be possible by breathing pure oxygen at standard air pressure. Amplifying oxygen in this way creates an environment that helps fight bacteria and triggers growth factors and stem cells for deep healing.
Principal mechanisms of HBO2 are based on intracellular generation of reactive species of oxygen and nitrogen. Reactive species are recognized to play a central role in cell signal transduction cascades and the discussion will focus on these pathways. Systematic reviews and randomized clinical trials support clinical use of HBO2 for refractory diabetic wound healing and radiation injuries; treatment of compromised flaps and grafts and ischemia-reperfusion disorders is supported by animal studies and a small number of clinical trials, but further studies are warranted.
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